Infectious Disease Biomarkers
A project to develop a simple test to rule out active tuberculosis
On presentation with symptoms of tuberculosis (TB), patients are immediately put onto strong antibiotics and it currently takes up to 6 weeks to determine whether or not this infection is present – and in the vast majority of cases it isn’t. A simple test to rule out active TB could have the potential to significantly change clinical practice both in the developed and developing world. This PoC project is supporting the development of a panel of RNA (and potentially protein) biomarkers which could not only rule out TB on presentation, but could be used to monitor disease progression once a patient is being treated.